Evidence reference only. Not medical advice, not a dosing guide, and not a recommendation to use any drug.
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The drug roster

40 medicines and 5 combination regimens. Class, physiology and reference records are kept out of this roster.

GLP-1 receptor agonists

18 agents

Semaglutide

MARKETED

GLP-1 receptor agonist

99 results + 2 ongoing View profile ->

Liraglutide

MARKETED

GLP-1 receptor agonist

35 results View profile ->

Dulaglutide

MARKETED

GLP-1 receptor agonist

23 results View profile ->

Exenatide

MIXED STATUS

Exendin-4-based GLP-1 receptor agonist

8 results View profile ->

Ecnoglutide

MARKETED

Long-acting cAMP-biased GLP-1 receptor agonist

5 results View profile ->

LY3537021

INVESTIGATIONAL

Selective long-acting GIP receptor agonist

5 results View profile ->

Lixisenatide

WITHDRAWN

Exendin-4-based GLP-1 receptor agonist

3 results View profile ->

Albiglutide

WITHDRAWN

GLP-1 receptor agonist

2 results View profile ->

Efpeglenatide

INVESTIGATIONAL

Exendin-based GLP-1 receptor agonist

2 results View profile ->

Monlunabant

INVESTIGATIONAL

Peripherally restricted cannabinoid CB1 receptor inverse agonist

2 results View profile ->

Bimagrumab

INVESTIGATIONAL

Activin type II receptor monoclonal antibody

1 results View profile ->

LY3463251

DISCONTINUED

Long-acting GDF15 receptor agonist acting through GFRAL and RET

1 results View profile ->

Resmetirom

MARKETED

Thyroid hormone receptor beta agonist

1 results View profile ->

Setmelanotide

MARKETED

Melanocortin-4 receptor agonist

1 results View profile ->

Apitegromab

INVESTIGATIONAL

Monoclonal antibody that inhibits activation of pro- and latent myostatin

0 results View profile ->

Enobosarm

INVESTIGATIONAL

Selective androgen receptor modulator

0 results View profile ->

Garetosmab

INVESTIGATIONAL

Activin A monoclonal antibody

0 results View profile ->

Trevogrumab

INVESTIGATIONAL

Myostatin monoclonal antibody

0 results View profile ->

Oral and small-molecule GLP-1

6 agents

Orforglipron

MARKETED

Oral non-peptide GLP-1 receptor agonist

20 results View profile ->

Danuglipron

DISCONTINUED

Oral non-peptide GLP-1 receptor agonist

5 results View profile ->

Aleniglipron

INVESTIGATIONAL

Oral non-peptide GLP-1 receptor agonist

4 results View profile ->

TERN-601

DISCONTINUED

Oral non-peptide GLP-1 receptor agonist

4 results View profile ->

Lotiglipron

DISCONTINUED

Oral non-peptide GLP-1 receptor agonist

3 results View profile ->

Elecoglipron

INVESTIGATIONAL

Oral non-peptide GLP-1 receptor agonist

1 results View profile ->

Combination regimens

5 agents

CagriSema

INVESTIGATIONAL

Long-acting amylin analogue combined with GLP-1 receptor agonism

14 results + 1 ongoing View profile ->

Bimagrumab plus semaglutide

INVESTIGATIONAL

Activin type II receptor inhibition combined with GLP-1 receptor agonism

2 results View profile ->

Apitegromab plus tirzepatide

INVESTIGATIONAL

Myostatin inhibition combined with GIP and GLP-1 receptor agonism

1 results View profile ->

Enobosarm plus semaglutide

INVESTIGATIONAL

Selective androgen receptor modulation combined with GLP-1 receptor agonism

1 results View profile ->

Trevogrumab plus semaglutide

INVESTIGATIONAL

Myostatin inhibition combined with GLP-1 receptor agonism

1 results View profile ->

GLP-1 / glucagon dual agonists

5 agents

Cotadutide

DISCONTINUED

GLP-1 and glucagon receptor dual agonist

14 results View profile ->

Survodutide

INVESTIGATIONAL

Glucagon and GLP-1 receptor dual agonist

14 results View profile ->

Pemvidutide

INVESTIGATIONAL

GLP-1 and glucagon receptor dual agonist

11 results View profile ->

Mazdutide

MARKETED

GLP-1 and glucagon receptor dual agonist

10 results + 2 ongoing View profile ->

Efinopegdutide

INVESTIGATIONAL

GLP-1 and glucagon receptor dual agonist

5 results View profile ->

GIP / GLP-1 dual agonists

4 agents

Tirzepatide

MARKETED

GIP and GLP-1 receptor dual agonist

82 results + 2 ongoing View profile ->

MariTide

INVESTIGATIONAL

GLP-1 receptor agonist and GIP receptor antagonist peptide-antibody conjugate

8 results View profile ->

Enicepatide

INVESTIGATIONAL

GIP and GLP-1 receptor dual agonist

6 results View profile ->

BI 3034701

INVESTIGATIONAL

GLP-1, GIP and neuropeptide Y2 receptor triple agonist

3 results View profile ->

Amylin and amylin combinations

4 agents

Cagrilintide

INVESTIGATIONAL

Long-acting amylin analogue

7 results View profile ->

Pramlintide

DISCONTINUED

Synthetic amylin analogue

6 results View profile ->

Amycretin

INVESTIGATIONAL

Unimolecular GLP-1 and amylin receptor agonist

5 results View profile ->

Petrelintide

INVESTIGATIONAL

Long-acting amylin analogue

5 results View profile ->

Triple agonists

3 agents

Retatrutide

INVESTIGATIONAL

GIP, GLP-1 and glucagon receptor triple agonist

52 results + 8 ongoing View profile ->

HM15275

INVESTIGATIONAL

GLP-1, GIP and glucagon receptor triple agonist

1 results View profile ->

Efocipegtrutide

INVESTIGATIONAL

GLP-1, GIP and glucagon receptor triple agonist

0 results + 2 ongoing View profile ->